TRIF-deficient Herpes simplex encephalitis patient: peripheral blood mononuclear cell response to TLR agonists LPS and R-848 - - GEO DataSets

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TRIF-deficient Herpes simplex encephalitis patient: peripheral blood mononuclear cell response to TLR agonists LPS and R-848

Analysis of PBMCs collected from an HSV1 encephalitis (HSE) patient with TRIF deficiency (homozygous TRIF nonsense mutation) and stimulated with LPS or resiquimod hydrochloride R-848. TRIF is the sole adaptor protein for TLR3. Results provide insight into the role of the TLR3 pathway in HSE.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent, 2 disease state, 3 genotype/variation sets

Platform:: GPL10558
Series:: GSE32390
9 Samples

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Accession:: GDS4540

ID:: 4540

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