GEO DataSet Links for PMC (Select 2933218) - GEO DataSets

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Items: 2

Select item 2000080961.

Transcription profiling time series of finite life span and immortal non-malignant human mammary epithelial cell lines

(Submitter supplied) Nonmalignant human mammary epithelial cells (HMEC) seeded in laminin-rich extracellular matrix (lrECM) form polarized acini and, in doing so, transit from a disorganized proliferating state to an organized growth-arrested state. We hypothesized that the gene expression pattern of organized and growth-arrested HMECs would share similarities with breast tumors with good prognoses. Using Affymetrix HG-U133A microarrays, we analyzed the expression of 22,283 gene transcripts in 184 (finite life span) and HMT3522 S1 (immortal nonmalignant) HMECs on successive days after seeding in a lrECM assay. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2810
Platform:: GPL96
12 Samples

Download data: CEL

Series

Accession:: GSE8096

ID:: 200008096

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 28102.

Organized and growth-arrested mammary acini: time course

Temporal analysis of two nonmalignant mammary epithelial cells (HMEC) grown in a laminin-rich extracellular matrix. Both HMECs transit from a disorganized to an organized state to form polarized acini. Results identify gene signatures with potential value for breast cancer prognosis prediction.