GEO DataSet Links for PMC (Select 3226404) - GEO DataSets

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Items: 2

Select item 2000305311.

Expression data of A375 melanoma cells after DMSO or MLN4924 treatment from 1 hour to 24 hour

(Submitter supplied) Microarrays were used to determine the change in gene expression of genes involved in the CDT1/NAE pathway

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4819
Platform:: GPL570
30 Samples

Download data: CEL

Series

Accession:: GSE30531

ID:: 200030531

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48192.

Inhibitor of NEDD8-activating enzyme MLN4924 effect on melanoma cell line

Analysis of A375 melanoma cells treated with small molecule MLN4924 for up to 24 hrs. MLN4924 selectively inhibits Nedd8-activating enzyme resulting in inactivation of the entire family of Cullin-RING ubiquitin ligases. Results provide insight into the molecular basis of MLN4924-induced cell death.