Expression data of inducible stable cell lines overexpressing Ero1alpha WT and Ero1alpha C104A/C131A - - GEO DataSets

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Expression data of inducible stable cell lines overexpressing Ero1alpha WT and Ero1alpha C104A/C131A

(Submitter supplied) The overall cellular response to oxidative stress generated by Ero1α in the lumen of the mammalian endoplasmic reticulum (ER) is poorly characterized. Here, we investigate the effects of overexpressing a hyperactive mutant (C104A/C131A) of Ero1α. Using microarray analysis, we demonstrate that the cell reacts to the oxidative challenge caused by Ero1α hyperactivity by turning on the unfolded protein response. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
12 Samples

Download data: CEL

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Accession:: GSE40601

ID:: 200040601

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