GEO DataSet Links for PMC (Select 3704950) - GEO DataSets

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Items: 2

Select item 2000443221.

Gene expression profile analysis of mouse whole spleen following infection by lymphocytic choriomeningitis virus (LCMV), comparing LCMV-Armstrong and LCMV-Clone 13 expression patterns at 0, 5, 9, and 30 days

(Submitter supplied) To identify mechanisms behind immunosuppression during virus infections, we infected mice with LCMV-Armstrong and LCMV-Clone 13 expression patterns. LCMV-Armstrong induces a T-cell reaction that resolves infection within 8-10 days, while LCMV-Clone13 generates a persisten infection through immunosuppression. We used microarray to uncover splenic gene expression patterns specific to each LCMV infection at 5, 9, and 30 days

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4556
Platform:: GPL6246
26 Samples

Download data: CEL

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Accession:: GSE44322

ID:: 200044322

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 45562.

Spleen response to acute LCMV-Armstrong and persistent LCMV-Clone13 infections: time course

Analysis of spleen infected with 2 strains of lymphocytic choriomeningitis virus. LCMV-Arm induces T-cell response that resolves infection within 10 days; LCMV-Cl13 induces persistent infection via immunosuppression. Results provide insight into molecular basis of virus-induced immunosuppression.