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Items: 2

1.

Strain-specific Innate Immune Signaling Pathways Determine Malaria Parasitemia Dynamics and Host Mortality

(Submitter supplied) Malaria infection triggers vigorous host immune responses; however, the parasite ligands, host receptors and the signaling pathways responsible for these reactions remain unknown or controversial. Malaria parasites primarily reside within red blood cells (RBCs), thereby hiding themselves from direct contact and recognition by host immune cells. Host responses to malaria infection are very different from those elicited by bacterial and viral infections and the host receptors recognizing parasite ligands have been elusive. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5225
Platform:
GPL6885
18 Samples
Download data: TXT
Series
Accession:
GSE51329
ID:
200051329
2.
Full record GDS5225

Spleen response to infection by Plasmodium yoelii strains N67 and N67C

Analysis of spleen from C57BL/6 females infected with Plasmodium yoelii strains N67 and N67C which produce different levels of disease severity. Results provide insight into host innate response pathways corresponding to strain-specific disease phenotypes.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 3 infection sets
Platform:
GPL6885
Series:
GSE51329
18 Samples
Download data: TXT

Supplemental Content

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