GEO DataSet Links for PMC (Select 3935234) - GEO DataSets

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Items: 2

Select item 2000507561.

Cyclophilin B supports the survuval of glioblastoma multiforme cells

(Submitter supplied) We have found that cyclophilin B (CypB) expression is important for malignant glioblastoma multiforme (GBM) cell proliferation. To identify molecular mechanisms that could explain CypB-dependent survival in human GBM cells, a microarray analysis was performed using RNA prepared from U251MG GBM cells transduced with lentiviral CypB shRNA. These data revealed that about 130 genes were more than 2-fold affected by CypB depletion. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4828
Platform:: GPL10558
6 Samples

Download data: TXT

Series

Accession:: GSE50756

ID:: 200050756

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48282.

Cyclophilin B depletion effect on glioblastoma multiforme cell line

Analysis of U251 glioblastoma multiforme (GBM) cells depleted for cyclophilin B (CypB), a prolyl isomerase in the endoplasmic reticulum. CypB depletion reduces GBM cell survival. Results provide insight into the role of CypB in the survival of GBM cells.