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Items: 2

1.

Expression data from yeast wild type (WT) and sod1Δ strains after treatment with hydrogen peroxide (H2O2)

(Submitter supplied) An important cellular defense mechanism against oxidative stress is the induction of genes involved in ROS resistance and DNA damage repair. Under normal conditions, Sod1 is localized mainly in the cytosol. However, we found that Sod1 translocates into the nucleus after oxidative stress. To address the physiological role of Sod1, we performed DNA microarray analysis of global gene expression in wild type (WT) and sod1Δ cells before and after treatment with H2O2.
Organism:
Saccharomyces cerevisiae; Schizosaccharomyces pombe
Type:
Expression profiling by array
Dataset:
GDS5630
Platform:
GPL2529
4 Samples
Download data: CEL
Series
Accession:
GSE55081
ID:
200055081
2.
Full record GDS5630

Hydrogen peroxide effect on superoxide dismutase 1-deficient yeast cells

Analysis of superoxide dismutase 1 deficient cells treated with reactive oxygen species hydrogen peroxide (H2O2) for 20 minutes. Sod1 deletion in yeast is known to cause extensive oxidative damage. Results provide insight into the molecular basis of Sod1’s role in oxidative stress resistance.
Organism:
Schizosaccharomyces pombe; Saccharomyces cerevisiae
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL2529
Series:
GSE55081
4 Samples
Download data: CEL

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