GEO DataSet Links for PMC (Select 7679990) - GEO DataSets

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Items: 2

Select item 2001482181.

Single cell characterization of arrested B-lymphoid differentiation and leukemic cell states in ETV6-RUNX1-positive pediatric leukemia

(Submitter supplied) Arrested bone marrow (BM) lymphoid cell differentiation underlies the emergence of the most common childhood cancer, acute lymphoblastic leukemia (ALL). Recurrent genetic lesions often directly involve transcription factors (TFs), such as ETV6 and RUNX1 found in the most common ALL translocation. Here, we studied differential gene expression in ETV6-RUNX1 primary ALL samples and the REH cell line using single cell RNA-seq (scRNA-seq). more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

4 related Platforms
15 Samples

Download data: BIGWIG, MTX, TSV

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Accession:: GSE148218

ID:: 200148218

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000675402.

RNA polymerase in pre-B-ALL cell lines

(Submitter supplied) [Gro-seq] Precursor B acute leukemia cells measured using global nuclear run-on sequencing [ChIP-Seq] The genome-wide occupancy of ser2 and ser5 phosphorylated RNA pol2 and H3K4me3 was measured in precursor B acute leukemia cells measured using chip-seq.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Third-party reanalysis; Genome binding/occupancy profiling by high throughput sequencing