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Typhoidal Salmonella Dendritic Cell Survival Mechanism Revealed by Dual RNA sequencing

(Submitter supplied) Salmonella enterica represent a major disease burden worldwide. While non-typhoidal Salmonella (NTS) serovars trigger self-limiting diarrhoea, leading to occasional secondary bacteraemia, S. enterica serovar Typhi is responsible for potentially life-threatening Typhoid fever. Dendritic cells (DCs) are key professional antigen presenting cells of the human immune system. The ability of pathogenic bacteria to subvert DC functions and prevent T cell recognition contributes to their survival and dissemination within the host. more...
Organism:
Homo sapiens; Salmonella enterica; Salmonella enterica subsp. enterica serovar Typhimurium str. LT2; Salmonella enterica subsp. enterica serovar Typhi str. Ty2; Salmonella enterica subsp. enterica serovar Typhimurium str. D23580
Type:
Expression profiling by high throughput sequencing
7 related Platforms
93 Samples
Download data: TXT
Series
Accession:
GSE161854
ID:
200161854

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