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Items: 3

1.

Integrated analyses reveal CHD4 mediating establishment and maintenance of latent KSHV chromatin

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Human gammaherpesvirus 8; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platform:
GPL25719
42 Samples
Download data: BW, HIC
Series
Accession:
GSE163695
ID:
200163695
2.

Integrated analyses reveal CHD4 mediating establishment and maintenance of latent KSHV chromatin [Capture Hi-C]

(Submitter supplied) lncRNAs regulate protein functions via formation of protein-RNA complexes. Previous studies have shown that expression of viral lncRNA, polyadenylated nuclear RNA (PAN RNA) is essential for inducible viral genomic looping and distal gene activation during Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation. Here we show an underlying molecular mechanism and regulation of KSHV latency by a viral lncRNA-CHD4 (chromodomain helicase DNA binding protein 4) interaction. more...
Organism:
Human gammaherpesvirus 8; Homo sapiens
Type:
Other
Platform:
GPL25719
12 Samples
Download data: HIC
Series
Accession:
GSE163694
ID:
200163694
3.

Integrated analyses reveal CHD4 mediating establishment and maintenance of latent KSHV chromatin [CUT&RUN]

(Submitter supplied) lncRNAs regulate protein functions via formation of protein-RNA complexes. Previous studies have shown that expression of viral lncRNA, polyadenylated nuclear RNA (PAN RNA) is essential for inducible viral genomic looping and distal gene activation during Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation. Here we show an underlying molecular mechanism and regulation of KSHV latency by a viral lncRNA-CHD4 (chromodomain helicase DNA binding protein 4) interaction. more...
Organism:
Homo sapiens; Human gammaherpesvirus 8
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL25719
30 Samples
Download data: BW
Series
Accession:
GSE163098
ID:
200163098
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