GEO DataSet Links for SRA (Select 11638041) - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Links from SRA

Items: 2

Select item 3047288911.

Aptamer21-PEARL-Cmpd5-Cmpd2d-None-1

Organism:: Synthetic plasmid

Source name:: In vitro transcription

Platform:: GPL20106
Series:: GSE156312

Download data: TXT

Sample

Accession:: GSM4728891

ID:: 304728891

SRA Run Selector

Select item 2001563122.

PEARL-seq: A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions

(Submitter supplied) RNA is emerging as a valuable target for the development of novel therapeutic agents. The rational design of RNA-targeting small molecules, however, has been hampered by the relative lack of methods for the analysis of small molecule-RNA interactions. Here we present our efforts to develop such a platform using photoaffinity labeling. This technique, termed Photoaffinity Evaluation of RNA Ligation-Sequencing (PEARL-seq), enables the rapid identification of small molecule binding locations within their RNA targets and can provide information on ligand selectivity across multiple different RNAs. more...