GEO DataSet Links for SRA (Select 5934867) - GEO DataSets

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Items: 2

Select item 3032621071.

hyphae_24 hrs_DMSO rep 1

Organism:: Aspergillus nidulans FGSC A4

Source name:: Hyphae

Platform:: GPL25307
Series:: GSE116804

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Accession:: GSM3262107

ID:: 303262107

SRA Run Selector

Select item 2001168042.

Cytochrome P450 Monooxygenase Mediated Metabolic Utilization of Benzo(a)pyrene by Fungi

(Submitter supplied) Soil dwelling Aspergillus fungi possess the versatile metabolic capability to utilize complex organic compounds which are toxic to humans, yet the mechanisms they employ remain largely unknown. Benzo(a)pyrene is a common carcinogenic contaminant, posing a significant concern for human health. Here, we report that Aspergillus fungi can degrade benzo(a)pyrene effectively. In Aspergillus nidulans, exposure to benzo(a)pyrene results in transcriptomic and metabolic changes associated with cellular growth and energy generation, implying that the fungus utilizes benzo(a)pyrene as a food. more...