GEO DataSets

(Submitter supplied) Primate evolution has been argued to result, in part, from changes in how genes are regulated. However, we still know little about gene regulation in natural primate populations. We conducted an RNA sequencing (RNA-seq)-based study of baboons from an intensively studied wild population. We performed complementary expression quantitative trait locus (eQTL) mapping and allele-specific expression analyses, discovering substantial evidence for, and surprising power to detect, genetic effects on gene expression levels in the baboons. more...

Organism:

Papio cynocephalus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL19769

63 Samples

Download data: TXT

(Submitter supplied) We present a comparison of four reference-based mapping methods for mapping non-human primate data to a human reference sequence. We utilize TopHat2 and GSNAP for mapping to the human genome, and Bowtie2 and Stampy for mapping to the human genome and transcriptome for a total of six mapping approaches

Organism:

Papio cynocephalus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18669

12 Samples

Download data: TXT

(Submitter supplied) Severe sepsis leads to massive activation of coagulation and complement cascades that could contribute to multiple organ failure (MOF) and death. To investigate the role of the complement and its crosstalk with the hemostatic system in the pathophysiology and therapeutics of sepsis, we have used a potent inhibitor (compstatin) administered early or late post E. coli challenge in a baboon model of sepsis-induced MOF. more...

Organism:

Papio cynocephalus; Homo sapiens

Type:

Expression profiling by array

Platform:

GPL571

23 Samples

Download data: CEL