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pvalb3 parvalbumin 3 [ Danio rerio (zebrafish) ]

Gene ID: 100000771, updated on 2-Nov-2024

Summary

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Official Symbol
pvalb3provided by ZNC
Official Full Name
parvalbumin 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-945
See related
Ensembl:ENSDARG00000022817 AllianceGenome:ZFIN:ZDB-GENE-040426-945
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56217; zgc:77798
Summary
Predicted to enable calcium ion binding activity. Predicted to be active in cytoplasm. Is expressed in hypaxial myotome region and myotome. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See pvalb3 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (17705220..17707517, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (17583342..17585643, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene CCZ1 homolog, vacuolar protein trafficking and biogenesis associated Neighboring gene parvalbumin 9 Neighboring gene microRNA mir-2192 Neighboring gene parvalbumin 2 Neighboring gene uncharacterized LOC137496810 Neighboring gene microRNA 338-2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Parvalbumin isoforms in zebrafish. Friedberg F. Mol Biol Rep, 2005 Sep. PMID 16172917
  2. Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Cambier S, et al. Environ Sci Technol, 2010 Jan 1. PMID 20039754
  3. Global Transcriptomic Analysis of Zebrafish Glucagon Receptor Mutant Reveals Its Regulated Metabolic Network. Kang Q, et al. Int J Mol Sci, 2020 Jan 22. PMID 31979106, Free PMC Article
  4. Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress. Ge G, et al. Int J Mol Sci, 2022 Jul 6. PMID 35886843, Free PMC Article
  5. Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome. Modrell MS, et al. Elife, 2017 Mar 27. PMID 28346141, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC56217, MGC77798

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
parvalbumin 3
Names
parvalbumin, beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200212.1 → NP_956506.1  parvalbumin 3 isoform 1b

    See identical proteins and their annotated locations for NP_956506.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046001
    UniProtKB/TrEMBL
    F6PCJ6, Q6P5K2, Q7ZT36
    Related
    ENSDARP00000031690.5, ENSDART00000034914.7
    Conserved Domains (2) summary
    cd00051
    Location:43 → 108
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:44 → 107
    EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    17705220..17707517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005169450.5 → XP_005169507.1  parvalbumin 3 isoform X1

    See identical proteins and their annotated locations for XP_005169507.1

    UniProtKB/TrEMBL
    F6PCJ6, Q6P5K2, Q7ZT36
    Related
    ENSDARP00000121670.1, ENSDART00000142427.2
    Conserved Domains (2) summary
    cd00051
    Location:43 → 108
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:44 → 107
    EF-hand_7; EF-hand domain pair

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394834.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    149734..152030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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