kat8 K(lysine) acetyltransferase 8 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: kat8provided by ZNC
Official Full Name: K(lysine) acetyltransferase 8provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7510
See related: Ensembl:ENSDARG00000027187 AllianceGenome:ZFIN:ZDB-GENE-030131-7510
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: myst1; zgc:66387; wu:fb22g02; wu:fj22d09
Summary: Predicted to enable histone acetyltransferase activity (H4-K16 specific); histone binding activity; and transcription coregulator activity. Acts upstream of or within primitive hemopoiesis. Predicted to be located in nucleus. Predicted to be part of MSL complex. Orthologous to human KAT8 (lysine acetyltransferase 8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (32681274..32688593)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (32549610..32556878)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb22g02.x1 (e-PCR)
- UniSTS:203067

AI397400 (e-PCR)
- UniSTS:206653

AW202802 (e-PCR)
- UniSTS:205731

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone H4K16 acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables histone acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables transcription coregulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within primitive hemopoiesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of MSL complex	IBA Inferred from Biological aspect of Ancestor more info
part_of NSL complex	IBA Inferred from Biological aspect of Ancestor more info
part_of NuA4 histone acetyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of chromatin	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: histone acetyltransferase KAT8

Names: MYST histone acetyltransferase 1

NP_997907.2

EC 2.3.1.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.