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slc7a8b solute carrier family 7 member 8b [ Danio rerio (zebrafish) ]

Gene ID: 100007990, updated on 14-Nov-2024

Summary

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Official Symbol
slc7a8bprovided by ZNC
Official Full Name
solute carrier family 7 member 8bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030616-586
See related
Ensembl:ENSDARG00000054343 AllianceGenome:ZFIN:ZDB-GENE-030616-586
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
slc7a8; si:zc14a17.3; si:ch211-14a17.3
Summary
Predicted to enable L-amino acid transmembrane transporter activity and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport and neutral amino acid transport. Predicted to act upstream of or within amino acid transport and transmembrane transport. Predicted to be located in basolateral plasma membrane and lateral plasma membrane. Orthologous to human SLC7A8 (solute carrier family 7 member 8). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See slc7a8b in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (38314711..38337206, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (38332193..38354881, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene zona pellucida glycoprotein 3f, tandem duplicate 2 Neighboring gene NEDD8 ubiquitin like modifier, like Neighboring gene adaptor related protein complex 1 subunit gamma 2 Neighboring gene protein arginine methyltransferase 5 Neighboring gene uncharacterized LOC137488018

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration. Takayama K, et al. Sci Rep, 2018 May 29. PMID 29844341, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within amino acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in lateral plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large neutral amino acids transporter small subunit 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Names
solute carrier family 7 (amino acid transporter light chain, L system), member 8
solute carrier family 7 (amino acid transporter light chain, L system), member 8b
zmp:0000000645
zmp:0000000781

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    38314711..38337206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467805.2 → XP_021323480.1  large neutral amino acids transporter small subunit 2

    UniProtKB/TrEMBL
    A0A8M9PMI3
    Conserved Domains (1) summary
    cl26159
    Location:9 → 488
    AA_permease_2; Amino acid permease

  2. XM_068214399.1 → XP_068070500.1  large neutral amino acids transporter small subunit 2

  3. XM_021467801.2 → XP_021323476.1  large neutral amino acids transporter small subunit 2

    UniProtKB/TrEMBL
    A0A8M9PMI3
    Related
    ENSDARP00000070995.4, ENSDART00000076523.5
    Conserved Domains (1) summary
    cl26159
    Location:9 → 488
    AA_permease_2; Amino acid permease

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394506.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    361724..380130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001346278.8 → XP_001346314.3  large neutral amino acids transporter small subunit 2

    UniProtKB/TrEMBL
    A0A8M9PMI3
    Conserved Domains (1) summary
    cl26159
    Location:9 → 488
    AA_permease_2; Amino acid permease

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001007184.1: Suppressed sequence

    Description
    NM_001007184.1: This RefSeq was permanently suppressed because there was insufficient support for the transcript.
Nucleotide Protein Strain
Heading Accession and Version

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