U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ncapg2 non-SMC condensin II complex, subunit G2 [ Danio rerio (zebrafish) ]

Gene ID: 100037337, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
ncapg2provided by ZNC
Official Full Name
non-SMC condensin II complex, subunit G2provided by ZNC
Primary source
ZFIN:ZDB-GENE-070410-100
See related
Ensembl:ENSDARG00000060023 AllianceGenome:ZFIN:ZDB-GENE-070410-100
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
CAP-G2; id:ibd2775; zgc:162881
Summary
Predicted to be involved in mitotic sister chromatid segregation. Predicted to act upstream of or within cell division and chromosome condensation. Predicted to be part of condensin complex. Predicted to be active in nucleus. Is expressed in brain and spinal cord. Orthologous to human NCAPG2 (non-SMC condensin II complex subunit G2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ncapg2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (40205410..40227607)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (39934377..39956586)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene dynein 2 intermediate chain 1 Neighboring gene extended synaptotagmin-like protein 2b Neighboring gene protein tyrosine phosphatase receptor type N2 Neighboring gene uncharacterized LOC137490295 Neighboring gene microRNA 153a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies. Khan TN, et al. Am J Hum Genet, 2019 Jan 3. PMID 30609410, Free PMC Article
  2. Dhx38 is required for the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing. Tu J, et al. Development, 2022 Sep 1. PMID 35929537
  3. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromosome condensation IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic sister chromatid segregation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of condensin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
condensin-2 complex subunit G2
Names
chromosome-associated protein G2
leucine zipper protein 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089492.3 → NP_001082961.3  condensin-2 complex subunit G2

    See identical proteins and their annotated locations for NP_001082961.3

    Status: VALIDATED

    Source sequence(s)
    BX248235, BX324185, CU467647
    UniProtKB/Swiss-Prot
    E7FH61, F8W2J6
    UniProtKB/TrEMBL
    A0A8M9QGK3
    Related
    ENSDARP00000124705.3, ENSDART00000148390.4
    Conserved Domains (2) summary
    sd00044
    Location:419 → 450
    HEAT; HEAT repeat [structural motif]
    pfam12422
    Location:213 → 361
    Condensin2nSMC; Condensin II non structural maintenance of chromosomes subunit

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    40205410..40227607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005166425.4 → XP_005166482.2  condensin-2 complex subunit G2 isoform X1

    See identical proteins and their annotated locations for XP_005166482.2

    UniProtKB/Swiss-Prot
    E7FH61, F8W2J6
    UniProtKB/TrEMBL
    A0A8M9QGK3
    Conserved Domains (2) summary
    sd00044
    Location:419 → 450
    HEAT; HEAT repeat [structural motif]
    pfam12422
    Location:213 → 361
    Condensin2nSMC; Condensin II non structural maintenance of chromosomes subunit

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394703.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    869..13057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E7FH61.2 GenPept UniProtKB/Swiss-Prot:E7FH61

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous