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Gm14295 predicted gene 14295 [ Mus musculus (house mouse) ]

Gene ID: 100039123, updated on 3-Apr-2024

Summary

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Official Symbol
Gm14295provided by MGI
Official Full Name
predicted gene 14295provided by MGI
Primary source
MGI:MGI:3709624
See related
Ensembl:ENSMUSG00000078877 AllianceGenome:MGI:3709624
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 6.2), frontal lobe adult (RPKM 6.2) and 22 other tissues See more
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Genomic context

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See Gm14295 in Genome Data Viewer
Location:
2 H4; 2 99.06 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (176489972..176512508)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (176798179..176814092)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 14305 Neighboring gene zinc finger protein 937 pseudogene Neighboring gene STARR-seq mESC enhancer starr_06660 Neighboring gene predicted gene 14408 Neighboring gene predicted gene 14405

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC100039123
Names
KRAB box and zinc finger, C2H2 type domain containing
novel KRAB box and zinc finger, C2H2 type domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205057.2 → NP_001191986.1  uncharacterized protein LOC100039123

    See identical proteins and their annotated locations for NP_001191986.1

    Status: VALIDATED

    Source sequence(s)
    BC083167, BC106197, CO428255
    Consensus CDS
    CCDS57201.1
    UniProtKB/TrEMBL
    A2BG90, J3QMJ8, Q8C1K5, Q8CFP2
    Related
    ENSMUSP00000113133.3, ENSMUST00000118012.9
    Conserved Domains (2) summary
    smart00349
    Location:4 → 45
    KRAB; krueppel associated box
    pfam01352
    Location:4 → 43
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    176489972..176512508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245890.2 → XP_030101750.1  uncharacterized protein LOC100039123 isoform X2

    UniProtKB/TrEMBL
    A2BG91
    Related
    ENSMUSP00000119262.2, ENSMUST00000132883.8
    Conserved Domains (4) summary
    COG5048
    Location:395 → 795
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:413 → 433
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 44
    KRAB; KRAB box
    pfam13465
    Location:118 → 142
    zf-H2C2_2; Zinc-finger double domain

  2. XM_030245886.2 → XP_030101746.1  uncharacterized protein LOC100039123 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:414 → 814
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:432 → 452
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:22 → 63
    KRAB; KRAB box
    pfam13465
    Location:137 → 161
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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