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Prss3l serine protease 3 like [ Mus musculus (house mouse) ]

Gene ID: 100040233, updated on 17-Aug-2024

Summary

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Official Symbol
Prss3lprovided by MGI
Official Full Name
serine protease 3 likeprovided by MGI
Primary source
MGI:MGI:3641889
See related
Ensembl:ENSMUSG00000071517 AllianceGenome:MGI:3641889
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm10334
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
6 B1; 6 19.58 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (41419150..41438162, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (41442214..41446097, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene T cell receptor beta chain Neighboring gene STARR-seq mESC enhancer starr_15698 Neighboring gene serine protease 1 (trypsin 1) like Neighboring gene Try10-like trypsinogen pseudogene Neighboring gene STARR-seq mESC enhancer starr_15699 Neighboring gene STARR-seq mESC enhancer starr_15700 Neighboring gene serine protease 1 (trypsin 1) Neighboring gene proline-rich polypeptide 3 pseudogene Neighboring gene serine protease 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement. Chen F, et al. J Immunol, 2001 Feb 1. PMID 11160223
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
  
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in collagen catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
mesotrypsin-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_006980.1 

    Range
    551420..555303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103153.2 → NP_001096623.1  mesotrypsin-like precursor

    See identical proteins and their annotated locations for NP_001096623.1

    Status: VALIDATED

    Source sequence(s)
    AC158659
    Consensus CDS
    CCDS39468.1
    UniProtKB/TrEMBL
    B9EJ35, Q792Y8
    Related
    ENSMUSP00000093698.6, ENSMUST00000095999.7
    Conserved Domains (1) summary
    cd00190
    Location:24 → 242
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  2. NM_001411837.1 → NP_001398766.1  mesotrypsin-like precursor

    Status: VALIDATED

    Source sequence(s)
    AC153854, AC158659
    UniProtKB/TrEMBL
    B9EJ35, Q792Y8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    41419150..41438162 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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