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Cyp2c69 cytochrome P450, family 2, subfamily c, polypeptide 69 [ Mus musculus (house mouse) ]

Gene ID: 100043108, updated on 27-Dec-2024

Summary

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Official Symbol
Cyp2c69provided by MGI
Official Full Name
cytochrome P450, family 2, subfamily c, polypeptide 69provided by MGI
Primary source
MGI:MGI:3721049
See related
Ensembl:ENSMUSG00000092008 AllianceGenome:MGI:3721049
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in liver adult (RPKM 247.6) and liver E18 (RPKM 141.3) See more
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Genomic context

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See Cyp2c69 in Genome Data Viewer
Location:
19 C3; 19 34.24 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (39831104..39875213, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (39842660..39886769, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 68 Neighboring gene STARR-seq mESC enhancer starr_46117 Neighboring gene STARR-seq mESC enhancer starr_46118 Neighboring gene STARR-seq mESC enhancer starr_46119 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 40 Neighboring gene STARR-seq mESC enhancer starr_46120 Neighboring gene STARR-seq mESC enhancer starr_46121 Neighboring gene STARR-seq mESC enhancer starr_46122 Neighboring gene STARR-seq mESC enhancer starr_46123 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 71, pseudogene Neighboring gene STARR-seq mESC enhancer starr_46124 Neighboring gene STARR-seq mESC enhancer starr_46125 Neighboring gene cytochrome P450, family 2. subfamily c, polypeptide 37

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in organic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in xenobiotic metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cytochrome P450, family 2, subfamily c, polypeptide 69

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104525.1 → NP_001097995.1  cytochrome P450, family 2, subfamily c, polypeptide 69 precursor

    Status: PROVISIONAL

    Source sequence(s)
    AC148006
    Consensus CDS
    CCDS50432.1
    UniProtKB/TrEMBL
    E9PXC3, Q8VCP4
    Related
    ENSMUSP00000132832.2, ENSMUST00000168838.3
    Conserved Domains (1) summary
    pfam00067
    Location:30 → 487
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    39831104..39875213 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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