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scaper S-phase cyclin A-associated protein in the ER [ Danio rerio (zebrafish) ]

Gene ID: 100144551, updated on 4-Jan-2025

Summary

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Official Symbol
scaperprovided by ZNC
Official Full Name
S-phase cyclin A-associated protein in the ERprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060303-5
See related
Ensembl:ENSDARG00000023104 AllianceGenome:ZFIN:ZDB-GENE-060303-5
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Orthologous to human SCAPER (S-phase cyclin A associated protein in the ER). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See scaper in Genome Data Viewer
Location:
chromosome: 25
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (32525065..32739728)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (32113926..32332664)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene sulfide quinone oxidoreductase Neighboring gene CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a Neighboring gene ISL LIM homeobox 2a Neighboring gene electron transfer flavoprotein subunit alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints. Irimia M, et al. Genome Res, 2012 Dec. PMID 22722344, Free PMC Article
  2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
S phase cyclin A-associated protein in the endoplasmic reticulum
Names
znf291

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123047.1 → NP_001116519.1  S phase cyclin A-associated protein in the endoplasmic reticulum

    See identical proteins and their annotated locations for NP_001116519.1

    Status: PROVISIONAL

    Source sequence(s)
    BC160657
    UniProtKB/TrEMBL
    A0A8M1NG13, B1H1L9
    Related
    ENSDARP00000094101.3, ENSDART00000103324.4
    Conserved Domains (6) summary
    smart00451
    Location:710 → 741
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:714 → 736
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00836
    Location:449 → 546
    Stathmin; Stathmin family
    pfam08597
    Location:298 → 393
    eIF3_subunit; Translation initiation factor eIF3 subunit
    pfam15665
    Location:466 → 687
    FAM184; Family with sequence similarity 184, A and B
    pfam16501
    Location:107 → 202
    SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    32525065..32739728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163154.5 → XP_005163211.4  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X1

    UniProtKB/TrEMBL
    A0A8M2BAB5
    Conserved Domains (4) summary
    smart00451
    Location:859 → 890
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:863 → 885
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16501
    Location:147 → 242
    SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    cl26511
    Location:494 → 839
    Neuromodulin_N; Gap junction protein N-terminal region

  2. XM_005163155.5 → XP_005163212.4  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X3

    UniProtKB/TrEMBL
    A0A8M2BA55
    Conserved Domains (4) summary
    smart00451
    Location:750 → 781
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:754 → 776
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam16501
    Location:147 → 242
    SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    cl26511
    Location:371 → 730
    Neuromodulin_N; Gap junction protein N-terminal region

  3. XM_005163156.4 → XP_005163213.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X2

    UniProtKB/TrEMBL
    A0A8M2BAI5
    Conserved Domains (5) summary
    smart00451
    Location:819 → 850
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:823 → 845
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00836
    Location:558 → 655
    Stathmin; Stathmin family
    pfam15665
    Location:575 → 796
    FAM184; Family with sequence similarity 184, A and B
    pfam16501
    Location:107 → 202
    SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
Nucleotide Protein Strain
Heading Accession and Version

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