si:dkey-73n8.3 si:dkey-73n8.3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: si:dkey-73n8.3provided by ZNC
Official Full Name: si:dkey-73n8.3provided by ZNC
Primary source: ZFIN:ZDB-GENE-141219-27
See related: Ensembl:ENSDARG00000089205 AllianceGenome:ZFIN:ZDB-GENE-141219-27
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable all-trans-retinol dehydrogenase (NADP+) activity. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 13 and Leber hereditary optic neuropathy. Orthologous to human RDH12 (retinol dehydrogenase 12). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

See si:dkey-73n8.3 in Genome Data Viewer

Location:: chromosome: 24

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (18470166..18477673, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (18325747..18333254, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables all-trans-retinol dehydrogenase (NADP+) activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC100150965

Names: retinol dehydrogenase 12-like

NP_001186991.1

EC 1.1.1.300

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001200062.1 → NP_001186991.1 uncharacterized protein LOC100150965

Status: PREDICTED

Source sequence(s)

BC122353, DT068986

UniProtKB/TrEMBL

A0A0R4IWU8, A0A8M1NXM3

Related

ENSDARP00000139421.1, ENSDART00000158393.2

Conserved Domains (2) summary

PRK06197
Location:19 → 295

PRK06197; short chain dehydrogenase; Provisional

cl21454
Location:20 → 287

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins