col28a2a collagen, type XXVIII, alpha 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: col28a2aprovided by ZNC
Official Full Name: collagen, type XXVIII, alpha 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4444
See related: Ensembl:ENSDARG00000076321 AllianceGenome:ZFIN:ZDB-GENE-030131-4444
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fd06c09; si:dkey-211m23.2
Summary: Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within cell adhesion. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in floor plate; integument; muscle; rhombomere 5; and white matter. Orthologous to human COL28A1 (collagen type XXVIII alpha 1 chain). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 36

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (48298473..48370606, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (48601078..48673211, complement)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables extracellular matrix structural constituent conferring tensile strength	IBA Inferred from Biological aspect of Ancestor more info
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in extracellular matrix organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of collagen trimer	IEA Inferred from Electronic Annotation more info
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: collagen, type XXVIII, alpha 2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001159842.2 → NP_001153314.2 collagen, type XXVIII, alpha 2a precursor

Status: VALIDATED

Source sequence(s)

CU182074

UniProtKB/TrEMBL

A0A8M1NUC2, F1QAB3

Related

ENSDARP00000100078.2, ENSDART00000115121.5

Conserved Domains (4) summary

pfam01391
Location:502 → 561

Collagen; Collagen triple helix repeat (20 copies)

pfam00014
Location:1151 → 1203

Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

pfam03157
Location:273 → 614

Glutenin_hmw; High molecular weight glutenin subunit

pfam00092
Location:817 → 995

VWA; von Willebrand factor type A domain