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ABCC6 ATP binding cassette subfamily C member 6 [ Bos taurus (domestic cattle) ]

Gene ID: 100337270, updated on 4-Oct-2024

Summary

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Official Symbol
ABCC6provided by VGNC
Official Full Name
ATP binding cassette subfamily C member 6provided by VGNC
Primary source
VGNC:VGNC:50200
See related
Ensembl:ENSBTAG00000015191
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See ABCC6 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (14481774..14553490, complement)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene rho-related GTP-binding protein RhoA-B-like Neighboring gene centrosomal protein 20 Neighboring gene ATP binding cassette subfamily C member 1 Neighboring gene uncharacterized LOC112444306 Neighboring gene BOS complex subunit NOMO1 Neighboring gene uncharacterized LOC132343847

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Bovine Genome Sequencing and Analysis Consortium, et al. Science, 2009 Apr 24. PMID 19390049, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
multidrug resistance-associated protein 6
Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
URG7 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276370.2 → NP_001263299.1  multidrug resistance-associated protein 6

    See identical proteins and their annotated locations for NP_001263299.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000025
    UniProtKB/TrEMBL
    G5E626
    Related
    ENSBTAP00000047017.3, ENSBTAT00000050284.5
    Conserved Domains (5) summary
    TIGR00957
    Location:14 → 1503
    MRP_assoc_pro; multi drug resistance-associated protein (MRP)
    cd03244
    Location:1264 → 1484
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:630 → 830
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    pfam16185
    Location:27 → 146
    MTABC_N; Mitochondrial ABC-transporter N-terminal five TM region
    cl00549
    Location:952 → 1215
    ABC_membrane; ABC transporter transmembrane region

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    14481774..14553490 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024984634.2 → XP_024840402.1  multidrug resistance-associated protein 6 isoform X1

    Conserved Domains (1) summary
    cl26602
    Location:14 → 1400
    SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

RNA

  1. XR_001495066.3 RNA Sequence

  2. XR_009492785.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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