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socs6 suppressor of cytokine signaling 6 [ Oncorhynchus mykiss (rainbow trout) ]

Gene ID: 100499596, updated on 14-Dec-2023

Summary

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Gene symbol
socs6
Gene description
suppressor of cytokine signaling 6
See related
Ensembl:ENSOMYG00000043493
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oncorhynchus mykiss
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
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Genomic context

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See socs6 in Genome Data Viewer
Location:
chromosome: 28
Exon count:
3
Annotation release Status Assembly Chr Location
101 current USDA_OmykA_1.1 (GCF_013265735.2) 28 NC_048592.1 (19391364..19394722, complement)
100 previous assembly Omyk_1.0 (GCF_002163495.1) 28 NC_035104.1 (19117734..19121085, complement)

Chromosome 28 - NC_048592.1Genomic Context describing neighboring genes Neighboring gene neuropilin and tolloid-like protein 1 Neighboring gene fATP synthase c subunit lysine N-methyltransferase Neighboring gene cerebellin-2-like Neighboring gene cysteine-rich secretory protein LCCL domain containing 1b Neighboring gene junctophilin-1 Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of suppressor of cytokine signalling (SOCS) 6, 7, 9 and CISH in rainbow trout Oncorhynchus mykiss and analysis of their expression in relation to other known trout SOCS. Wang T, et al. Fish Shellfish Immunol, 2010 Oct. PMID 20600958
  2. The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates. Berthelot C, et al. Nat Commun, 2014 Apr 22. PMID 24755649, Free PMC Article
  3. Characterization of the rainbow trout transcriptome using Sanger and 454-pyrosequencing approaches. Salem M, et al. BMC Genomics, 2010 Oct 13. PMID 20942956, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Four new members of the SOCS family of molecules in rainbow trout (Oncorhynchus mykiss), CISH and SOCS6, 7 and 9, are described for the first time in this species
    Title: Identification of suppressor of cytokine signalling (SOCS) 6, 7, 9 and CISH in rainbow trout Oncorhynchus mykiss and analysis of their expression in relation to other known trout SOCS.
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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of growth IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195173.1 → NP_001182102.1  suppressor of cytokine signaling 6

    See identical proteins and their annotated locations for NP_001182102.1

    Status: PROVISIONAL

    Source sequence(s)
    AM903342
    UniProtKB/TrEMBL
    D0IN13, D0IN15
    Related
    ENSOMYP00000095389.2, ENSOMYT00000103669.2
    Conserved Domains (2) summary
    cd10387
    Location:353 → 452
    SH2_SOCS6; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03740
    Location:475 → 515
    SOCS_SOCS6; SOCS (suppressors of cytokine signaling) box of SOCS6-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...

RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference USDA_OmykA_1.1 Primary Assembly

Genomic

  1. NC_048592.1 Reference USDA_OmykA_1.1 Primary Assembly

    Range
    19391364..19394722 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021588589.2 → XP_021444264.2  suppressor of cytokine signaling 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C7WHM8, D0IN15
    Conserved Domains (2) summary
    cd10387
    Location:353 → 452
    SH2_SOCS6; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03740
    Location:475 → 515
    SOCS_SOCS6; SOCS (suppressors of cytokine signaling) box of SOCS6-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...

  2. XM_021588590.2 → XP_021444265.2  suppressor of cytokine signaling 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C7WHM8, D0IN15
    Conserved Domains (2) summary
    cd10387
    Location:353 → 452
    SH2_SOCS6; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03740
    Location:475 → 515
    SOCS_SOCS6; SOCS (suppressors of cytokine signaling) box of SOCS6-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...

  3. XM_036965883.1 → XP_036821778.1  suppressor of cytokine signaling 6 isoform X1

    UniProtKB/TrEMBL
    A0A8C7WHM8, D0IN15
    Conserved Domains (2) summary
    cd10387
    Location:353 → 452
    SH2_SOCS6; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03740
    Location:475 → 515
    SOCS_SOCS6; SOCS (suppressors of cytokine signaling) box of SOCS6-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the ...
Nucleotide Protein
Heading Accession and Version

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