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MIR3650 microRNA 3650 [ Homo sapiens (human) ]

Gene ID: 100500824, updated on 17-Sep-2024

Summary

Official Symbol
MIR3650provided by HGNC
Official Full Name
microRNA 3650provided by HGNC
Primary source
HGNC:HGNC:38981
See related
Ensembl:ENSG00000265304 miRBase:MI0016050; AllianceGenome:HGNC:38981
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR3650 in Genome Data Viewer
Location:
5p13.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (38557502..38557561, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (38806579..38806638, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (38557604..38557663, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene EGF like, fibronectin type III and laminin G domains Neighboring gene uncharacterized LOC105374732 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:38463193-38464392 Neighboring gene uncharacterized LOC124900964 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr5:38466368-38467567 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:38468935-38469806 Neighboring gene LIF receptor subunit alpha Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:38556889-38557672 Neighboring gene uncharacterized LOC105374735 Neighboring gene LIFR antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 9095 Neighboring gene OSMR divergent transcript Neighboring gene long intergenic non-protein coding RNA 1265

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_037423.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC091823
    Related
    ENST00000581972.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    38557502..38557561 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    38806579..38806638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)