U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LINC00844 long intergenic non-protein coding RNA 844 [ Homo sapiens (human) ]

Gene ID: 100507008, updated on 10-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
LINC00844provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 844provided by HGNC
Primary source
HGNC:HGNC:45031
See related
AllianceGenome:HGNC:45031
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in liver (RPKM 38.5), brain (RPKM 22.9) and 2 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LINC00844 in Genome Data Viewer
Location:
10q21.1
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (58999518..59001617)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (59853507..59855606)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (60759278..60761377)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene BicC family RNA binding protein 1 Neighboring gene family with sequence similarity 133, member A pseudogene Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:60566642-60567841 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:60615945-60617144 Neighboring gene RN7SK pseudogene 196 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:60679234-60680433 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:60723235-60723736 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:60723737-60724236 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:60727069-60727982 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2381 Neighboring gene uncharacterized LOC102724768 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 10

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells. Li D, et al. Arch Toxicol, 2020 May. PMID 32222775, Free PMC Article
  2. Novel lncRNA LINC00844 Regulates Prostate Cancer Cell Migration and Invasion through AR Signaling. Lingadahalli S, et al. Mol Cancer Res, 2018 Dec. PMID 30115758
  3. LINC00844 suppresses tumor progression and predicts survival outcomes through inhibiting miR-19a-5p in cholangiocarcinoma. Zhang L, et al. Clin Transl Oncol, 2024 Feb. PMID 37400667
  4. Long intergenic noncoding RNA 00844 promotes apoptosis and represses proliferation of prostate cancer cells through upregulating GSTP1 by recruiting EBF1. Qiu K, et al. J Cell Physiol, 2020 Nov. PMID 32329523
  5. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Wang AG, et al. Biochem Biophys Res Commun, 2006 Jul 7. PMID 16712791

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC00844 suppresses tumor progression and predicts survival outcomes through inhibiting miR-19a-5p in cholangiocarcinoma.
    Title: LINC00844 suppresses tumor progression and predicts survival outcomes through inhibiting miR-19a-5p in cholangiocarcinoma.
  2. Long intergenic noncoding RNA 00844 promotes apoptosis and represses proliferation of prostate cancer cells through upregulating GSTP1 by recruiting EBF1.
    Title: Long intergenic noncoding RNA 00844 promotes apoptosis and represses proliferation of prostate cancer cells through upregulating GSTP1 by recruiting EBF1.
  3. The expression of LINC00844 is higher in normal prostate compared with malignant and metastatic prostate cancer tumors, and patients with low expression had a poor prognosis, suggesting LINC00844 functions in suppressing tumor progression and metastasis. Further highlights the function of the LINC00844 in regulating global AR-regulated genes in prostate cancer by modulating AR binding to chromatin.
    Title: Novel lncRNA LINC00844 Regulates Prostate Cancer Cell Migration and Invasion through AR Signaling.
Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_108046.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC022539, CB157564, DA153602, DB500612

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    58999518..59001617
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    59853507..59855606
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials