U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SPDYE16 speedy/RINGO cell cycle regulator family member E16 [ Homo sapiens (human) ]

Gene ID: 102723555, updated on 14-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
SPDYE16provided by HGNC
Official Full Name
speedy/RINGO cell cycle regulator family member E16provided by HGNC
Primary source
HGNC:HGNC:51512
See related
Ensembl:ENSG00000185040 AllianceGenome:HGNC:51512
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in testis (RPKM 3.6), skin (RPKM 1.1) and 24 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SPDYE16 in Genome Data Viewer
Location:
7q11.23
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (76531313..76543297, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (77810549..77822535, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (76160630..76172614, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76114631-76115532 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76115533-76116434 Neighboring gene uncharacterized LOC124901675 Neighboring gene farnesyl diphosphate synthase pseudogene 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:76138251-76138456 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76139334-76139906 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76139907-76140479 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76141233-76141884 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76142537-76143186 Neighboring gene deltex E3 ubiquitin ligase 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:76141885-76142536 Neighboring gene uroplakin 3B Neighboring gene long intergenic non-protein coding RNA 3009 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:76234980-76235481 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:76235482-76235982 Neighboring gene 7q11.23 distal recombination region Neighboring gene ReSE screen-validated silencer GRCh37_chr7:76261368-76261573 Neighboring gene POM121 and ZP3 fusion Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:76302620-76303188 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:76357185-76358384 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:76513437-76513979 Neighboring gene uncharacterized LOC105375358

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
speedy protein E16
Names
WBSCR19-like protein 5-like
putative speedy protein E16

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001351597.1 → NP_001338526.1  speedy protein E16 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC004980
    UniProtKB/Swiss-Prot
    A6NJR5
    Related
    ENSP00000488825.1, ENST00000515340.2
    Conserved Domains (1) summary
    pfam11357
    Location:154 → 308
    Spy1; Cell cycle regulatory protein

  2. NM_001394943.1 → NP_001381872.1  speedy protein E16 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC004980
    Consensus CDS
    CCDS94129.1
    UniProtKB/Swiss-Prot
    A6NNV3
    UniProtKB/TrEMBL
    A0A0J9YWM7
    Related
    ENSP00000487772.2, ENST00000633306.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    76531313..76543297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017012887.3 → XP_016868376.1  speedy protein E16 isoform X1

    UniProtKB/Swiss-Prot
    A6NJR5
    Conserved Domains (1) summary
    pfam11357
    Location:154 → 308
    Spy1; Cell cycle regulatory protein

  2. XM_047419718.1 → XP_047275674.1  speedy protein E16 isoform X2

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187561.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    18207..30134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054328698.1 → XP_054184673.1  speedy protein E16 isoform X4

    UniProtKB/TrEMBL
    A0A0J9YYB4

  2. XM_054328697.1 → XP_054184672.1  speedy protein E16 isoform X3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    77810549..77822535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054356996.1 → XP_054212971.1  speedy protein E16 isoform X1

    UniProtKB/TrEMBL
    A0A0J9YW45

  2. XM_054356997.1 → XP_054212972.1  speedy protein E16 isoform X5

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6NNV3.4 GenPept UniProtKB/Swiss-Prot:A6NNV3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials