U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SERPINA1 serpin family A member 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105856770, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
SERPINA1
Gene description
serpin family A member 1
See related
Ensembl:ENSMICG00000016415
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SERPINA1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 3 NC_033662.1 (5662693..5673976, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012199464.1 (1698238..1709522, complement)

Chromosome 3 - NC_033662.1Genomic Context describing neighboring genes Neighboring gene alpha-1-antitrypsin-like Neighboring gene uncharacterized LOC105856769 Neighboring gene serpin family A member 11 Neighboring gene serpin family A member 9

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema. Borel F, et al. Proc Natl Acad Sci U S A, 2018 Mar 13. PMID 29453277, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Serpina1 null mice develop emphysema spontaneously, similar to human disease phenotype.
    Title: Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
alpha-1-antitrypsin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033662.1 Reference Mmur_3.0 Primary Assembly

    Range
    5662693..5673976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012738632.2 → XP_012594086.1  alpha-1-antitrypsin

    See identical proteins and their annotated locations for XP_012594086.1

    UniProtKB/TrEMBL
    A0A8B7EIL3, A0A8C5V8G8
    Related
    ENSMICP00000014957.2, ENSMICT00000016411.3
    Conserved Domains (1) summary
    cd02056
    Location:53 → 410
    alpha-1-antitrypsin_like; alpha-1-antitrypsin_like. This family contains a variety of different members of clade A of the serpin superfamily. They include the classical serine proteinase inhibitors, alpha-1-antitrypsin and alpha-1-antichymotrypsin, protein C inhibitor, ...

  2. XM_012738631.2 → XP_012594085.1  alpha-1-antitrypsin

    See identical proteins and their annotated locations for XP_012594085.1

    UniProtKB/TrEMBL
    A0A8B7EIL3, A0A8C5V8G8
    Conserved Domains (1) summary
    cd02056
    Location:53 → 410
    alpha-1-antitrypsin_like; alpha-1-antitrypsin_like. This family contains a variety of different members of clade A of the serpin superfamily. They include the classical serine proteinase inhibitors, alpha-1-antitrypsin and alpha-1-antichymotrypsin, protein C inhibitor, ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.