U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105865896, updated on 16-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
SAMHD1
Gene description
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
See related
Ensembl:ENSMICG00000002446
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SAMHD1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 18 NC_033677.1 (15484806..15537277)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012203129.1 (3694322..3746869)

Chromosome 18 - NC_033677.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105865898 Neighboring gene RB transcriptional corepressor like 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene TBC/LysM-associated domain containing 2 Neighboring gene microtubule crosslinking factor 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Laguette N, et al. Cell Host Microbe, 2012 Feb 16. PMID 22305291, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dGTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dGTP catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Names
SAM domain and HD domain-containing protein
NP_001296877.1
XP_012610326.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001309948.1 → NP_001296877.1  deoxynucleoside triphosphate triphosphohydrolase SAMHD1

    See identical proteins and their annotated locations for NP_001296877.1

    Status: PROVISIONAL

    Source sequence(s)
    JN936914
    UniProtKB/TrEMBL
    A0A8C5URF9, K4K7U4
    Related
    ENSMICP00000002235.3, ENSMICT00000002449.3
    Conserved Domains (4) summary
    cd09508
    Location:41 → 110
    SAM_HD; SAM domain of HD-phosphohydrolase
    smart00454
    Location:43 → 107
    SAM; Sterile alpha motif
    COG1078
    Location:115 → 502
    YdhJ; HD superfamily phosphohydrolase [General function prediction only]
    cd00077
    Location:162 → 336
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif

RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033677.1 Reference Mmur_3.0 Primary Assembly

    Range
    15484806..15537277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012754872.2 → XP_012610326.1  deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1

    UniProtKB/TrEMBL
    A0A8B7FPL7, A0A8C5URF9
    Conserved Domains (4) summary
    cd09508
    Location:74 → 143
    SAM_HD; SAM domain of HD-phosphohydrolase
    smart00454
    Location:76 → 140
    SAM; Sterile alpha motif
    COG1078
    Location:148 → 568
    YdhJ; HD superfamily phosphohydrolase [General function prediction only]
    cd00077
    Location:195 → 369
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.