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TYROBP transmembrane immune signaling adaptor TYROBP [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105876902, updated on 13-Mar-2024

Summary

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Gene symbol
TYROBP
Gene description
transmembrane immune signaling adaptor TYROBP
See related
Ensembl:ENSMICG00000032551
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Also known as
DAP12
Orthologs
human mouse all
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Genomic context

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See TYROBP in Genome Data Viewer
Location:
chromosome: 22
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 22 NC_033681.1 (25240217..25242779)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012196797.1 (2818819..2821380)

Chromosome 22 - NC_033681.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat and fibronectin type III domain containing 3 Neighboring gene 40S ribosomal protein S29 pseudogene Neighboring gene hematopoietic cell signal transducer Neighboring gene NFKB inhibitor delta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel system of polymorphic and diverse NK cell receptors in primates. Averdam A, et al. PLoS Genet, 2009 Oct. PMID 19834558, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in microglial cell activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of B cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transforming growth factor beta1 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage fusion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of microglial cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of natural killer cell activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TYRO protein tyrosine kinase-binding protein
Names
TYRO protein tyrosine kinase binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001309947.1 → NP_001296876.1  TYRO protein tyrosine kinase-binding protein precursor

    See identical proteins and their annotated locations for NP_001296876.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ882077
    UniProtKB/TrEMBL
    A0A8C5XH60, D1GFC4
    Related
    ENSMICP00000021996.1, ENSMICT00000027487.2

RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033681.1 Reference Mmur_3.0 Primary Assembly

    Range
    25240217..25242779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012774982.2 → XP_012630436.1  TYRO protein tyrosine kinase-binding protein isoform X1

    See identical proteins and their annotated locations for XP_012630436.1

    UniProtKB/TrEMBL
    A0A8C5XH60, D1GFC3
    Related
    ENSMICP00000048651.1, ENSMICT00000070378.1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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