Apoc2l apolipoprotein C2 like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Apoc2lprovided by MGI
Official Full Name: apolipoprotein C2 likeprovided by MGI
Primary source: MGI:MGI:5753381
See related: Ensembl:ENSMUSG00000109350 AllianceGenome:MGI:5753381
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm44805; Apoc4-apoc2
Summary: This locus represents naturally occurring read-through transcription between the neighboring apolipoprotein C-IV (Apoc4) and apolipoprotein C-II (Apoc2) genes on chromosome 7. The readthrough transcript encodes a protein that shares sequence identity with the downstream gene (Apoc2). [provided by RefSeq, Jun 2015]
Expression: Biased expression in duodenum adult (RPKM 646.2), liver E18 (RPKM 538.9) and 6 other tissues See more
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Genomic context

Location:: 7 A3; 7

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (19405504..19415385, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (19671579..19681460, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables lipase inhibitor activity	ISO Inferred from Sequence Orthology more info
enables lipid binding	ISO Inferred from Sequence Orthology more info
enables lipoprotein lipase activator activity	ISO Inferred from Sequence Orthology more info
enables molecular function activator activity	ISO Inferred from Sequence Orthology more info
enables phospholipase activator activity	ISO Inferred from Sequence Orthology more info
enables phospholipase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cholesterol efflux	ISO Inferred from Sequence Orthology more info
involved_in chylomicron remnant clearance	ISO Inferred from Sequence Orthology more info
involved_in high-density lipoprotein particle clearance	ISO Inferred from Sequence Orthology more info
involved_in lipoprotein transport	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cholesterol transport	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of lipid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of receptor-mediated endocytosis	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of very-low-density lipoprotein particle clearance	ISO Inferred from Sequence Orthology more info
involved_in phospholipid efflux	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of fatty acid biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of lipoprotein lipase activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of phospholipase activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of phospholipid catabolic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of triglyceride catabolic process	ISO Inferred from Sequence Orthology more info
involved_in triglyceride homeostasis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of chylomicron	ISO Inferred from Sequence Orthology more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
part_of intermediate-density lipoprotein particle	ISO Inferred from Sequence Orthology more info
part_of low-density lipoprotein particle	ISO Inferred from Sequence Orthology more info
part_of spherical high-density lipoprotein particle	ISO Inferred from Sequence Orthology more info
part_of very-low-density lipoprotein particle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: apolipoprotein C-II

Names: Apoc4-Apoc2 readthrough

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.