U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC110120389 VISTA enhancer mm567 [ Mus musculus (house mouse) ]

Gene ID: 110120389, updated on 9-Aug-2024

Summary

Go to the top of the page Help
Gene symbol
LOC110120389
Gene description
VISTA enhancer mm567
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr1334
Summary
This locus includes a conserved genomic element that can function as an enhancer. It can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic heart of transgenic mice. An overlapping subregion was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Sep 2023]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC110120389 in Genome Data Viewer
Location:
7; 7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (19053332..19054295)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (19319407..19320266)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1082 Neighboring gene nuclear encoded tRNA selenocysteine 2 (anticodon TCA) Neighboring gene STARR-positive B cell enhancer ABC_E9021 Neighboring gene STARR-positive B cell enhancer ABC_E11736 Neighboring gene FBJ osteosarcoma oncogene B Neighboring gene RIKEN cDNA D830036C21 gene Neighboring gene STARR-positive B cell enhancer ABC_E10427 Neighboring gene STARR-positive B cell enhancer ABC_E1719 Neighboring gene excision repair cross-complementing rodent repair deficiency, complementation group 1 Neighboring gene STARR-positive B cell enhancer ABC_E6519 Neighboring gene RNA polymerase I subunit G Neighboring gene STARR-seq mESC enhancer starr_18201 Neighboring gene protein phosphatase 1, regulatory subunit 13 like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. VISTA Enhancer Browser--a database of tissue-specific human enhancers. Visel A, et al. Nucleic Acids Res, 2007 Jan. PMID 17130149, Free PMC Article
  2. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  3. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Other Names

  • STARR-positive B cell enhancer ABC_E6518
  • regulatory region 1334

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054452.2 

    Range
    101..1064
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    19053332..19054295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version