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LOC111188155 Csf1r promoter/intronic regulatory region [ Mus musculus (house mouse) ]

Gene ID: 111188155, updated on 9-Aug-2024

Summary

Gene symbol
LOC111188155
Gene description
Csf1r promoter/intronic regulatory region
Gene type
biological region
Feature type(s)
protein_bind
regulatory: DNase_I_hypersensitive_site, enhancer, promoter, transcriptional_cis_regulatory_region
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FIRE
Summary
This region encompasses the macrophage promoter as well as downstream regulatory regions of the colony stimulating factor 1 receptor (Csf1r) gene, also known as c-fms. This sequence includes DNaseI hypersensitive sites corresponding to the proximal promoter and to enhancer elements located in an intron region. One of these enhancer elements, known as FIRE (fms intronic regulatory element), can also function as an antisense promoter that may produce transcripts that regulate expression of Csf1r. The proximal promoter and intronic FIRE element are regulated through binding by Spi-1 proto-oncogene, Sp1/Sp3 transcription factors, runt related transcription factor 1, and paired box 5 to recognition sites in this sequence. [provided by RefSeq, Sep 2017]
Orthologs
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Genomic context

See LOC111188155 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (61235478..61242699)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (61102406..61109627)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene caudal type homeobox 1 Neighboring gene predicted gene, 52351 Neighboring gene platelet derived growth factor receptor, beta polypeptide Neighboring gene colony stimulating factor 1 receptor Neighboring gene microRNA 6983 Neighboring gene HMG box domain containing 3 Neighboring gene predicted gene, 26403

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_055558.1 

    Range
    101..7322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    61235478..61242699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)