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LINC00310 long intergenic non-protein coding RNA 310 [ Homo sapiens (human) ]

Gene ID: 114036, updated on 17-Sep-2024

Summary

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Official Symbol
LINC00310provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 310provided by HGNC
Primary source
HGNC:HGNC:16414
See related
Ensembl:ENSG00000227456 AllianceGenome:HGNC:16414
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C21orf82; NCRNA00310
Expression
Low expression observed in reference dataset See more
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Genomic context

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See LINC00310 in Genome Data Viewer
Location:
21q22.11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (34180677..34189919)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (32562758..32572000)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (35552978..35562220)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:35445789-35446739 Neighboring gene solute carrier family 5 member 3 Neighboring gene mitochondrial ribosomal protein S6 Neighboring gene H3K27ac hESC enhancer GRCh37_chr21:35501946-35502490 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:35531196-35531696 Neighboring gene RPS5 pseudogene 2 Neighboring gene NANOG hESC enhancer GRCh37_chr21:35551498-35552375 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18394 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35575958-35576956 Neighboring gene VISTA enhancer hs2174 Neighboring gene uncharacterized LOC105372791 Neighboring gene Sharpr-MPRA regulatory region 13847 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35755873-35756380 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35756381-35756886 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35756972-35757494 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:35757495-35758015 Neighboring gene potassium voltage-gated channel subfamily E regulatory subunit 2 Neighboring gene small integral membrane protein 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell]. Ma S, et al. Wei Sheng Yan Jiu, 2020 Sep. PMID 33070810
  2. The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer. Li J, et al. J Cell Mol Med, 2018 Sep. PMID 29993199, Free PMC Article
  3. Nineteen additional unpredicted transcripts from human chromosome 21. Reymond A, et al. Genomics, 2002 Jun. PMID 12036297
  4. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell].
    Title: [Role of LINC00310 in the glycidyl methacrylate-induced malignant transformation of human bronchial epithelial cell].
  2. Long non-coding RNA LINC00310 promoted cell proliferation by regulating c-Myc expression in vitro.
    Title: The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

Clone Names

  • FLJ35385, MGC138201

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_027266.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AF426258, AK092704

  2. NR_027267.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 3' exon, compared to variant 1.
    Source sequence(s)
    AF426258
    Related
    ENST00000428914.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    34180677..34189919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    32562758..32572000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_153751.1: Suppressed sequence

    Description
    NM_153751.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P59036.1 GenPept UniProtKB/Swiss-Prot:P59036

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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