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optn optineurin [ Scophthalmus maximus (turbot) ]

Gene ID: 118319497, updated on 20-Mar-2024

Summary

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Gene symbol
optn
Gene description
optineurin
See related
EnsemblRapid:ENSSMAG00025005517
Gene type
protein coding
RefSeq status
MODEL
Organism
Scophthalmus maximus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae; Scophthalmus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 12
Exon count:
14
Annotation release Status Assembly Chr Location
101 current ASM2237912v1 (GCF_022379125.1) 12 NC_061526.1 (11175652..11184259, complement)
100 previous assembly ASM1334776v1 (GCF_013347765.1) 2 NC_049689.1 (11357411..11366018, complement)

Chromosome 12 - NC_061526.1Genomic Context describing neighboring genes Neighboring gene upper zone of growth plate and cartilage matrix associated a Neighboring gene minichromosome maintenance 10 replication initiation factor Neighboring gene uncharacterized LOC124849345 Neighboring gene coiled-coil domain containing 3a Neighboring gene calcium/calmodulin-dependent protein kinase 1Da

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-throughput sequence analysis of turbot (Scophthalmus maximus) transcriptome using 454-pyrosequencing for the discovery of antiviral immune genes. Pereiro P, et al. PLoS One, 2012. PMID 22629298, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi ribbon formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
optineurin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Scophthalmus maximus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2237912v1 Primary Assembly

Genomic

  1. NC_061526.1 Reference ASM2237912v1 Primary Assembly

    Range
    11175652..11184259 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035649947.2 → XP_035505840.1  optineurin isoform X1

    Related
    ENSSMAP00025017446.1, ENSSMAT00025018297.1
    Conserved Domains (4) summary
    COG1196
    Location:213 → 490
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam11577
    Location:57 → 120
    NEMO; NF-kappa-B essential modulator NEMO
    pfam18414
    Location:542 → 567
    zf_C2H2_10; C2H2 type zinc-finger
    pfam16516
    Location:404 → 496
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator

  2. XM_035649956.2 → XP_035505849.1  optineurin isoform X2

    UniProtKB/TrEMBL
    A0A2U9B1U3
    Related
    ENSSMAP00025017442.1, ENSSMAT00025018293.1
    Conserved Domains (4) summary
    COG1196
    Location:178 → 416
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam11577
    Location:22 → 85
    NEMO; NF-kappa-B essential modulator NEMO
    pfam18414
    Location:507 → 532
    zf_C2H2_10; C2H2 type zinc-finger
    pfam16516
    Location:369 → 461
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
Nucleotide Protein Strain
Heading Accession and Version

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