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LOC126805882 BRD4-independent group 4 enhancer GRCh37_chr1:157593763-157594962 [ Homo sapiens (human) ]

Gene ID: 126805882, updated on 12-Sep-2024

Summary

Gene symbol
LOC126805882
Gene description
BRD4-independent group 4 enhancer GRCh37_chr1:157593763-157594962
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the STARR-seq (self-transcribing active regulatory region sequencing) massively parallel reporter assay in HCT116 colorectal carcinoma cells. This sequence was defined as a group 4 enhancer that depends on the BRD2, P300/CBP, MED14 and CDK7 cofactors, but it has limited or no dependence on the BRD4 bromodomain protein. [provided by RefSeq, Sep 2022]
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Genomic context

See LOC126805882 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (157623973..157625172)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (156761014..156762213)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (157593763..157594962)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:157489840-157491039 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1891 Neighboring gene Fc receptor like 5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1892 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:157556896-157558095 Neighboring gene Fc receptor like 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1447 Neighboring gene uncharacterized LOC105371457 Neighboring gene Fc receptor like 3

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_082206.1 

    Range
    101..1300
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    157623973..157625172
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    156761014..156762213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)