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LOC127267030 H3K27ac hESC enhancer GRCh37_chr1:3541953-3542615 [ Homo sapiens (human) ]

Gene ID: 127267030, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127267030
Gene description
H3K27ac hESC enhancer GRCh37_chr1:3541953-3542615
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (3625389..3626051)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (3135484..3136146)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 6 Neighboring gene uncharacterized LOC105378608 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:3493527-3494026 Neighboring gene microRNA 551a Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:3506712-3507277 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:3507278-3507842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:3508323-3509002 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:3513146-3514042 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:3529609-3530355 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:3530356-3531101 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:3535070-3535978 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 60 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 121 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:3557544-3558044 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:3558876-3559121 Neighboring gene tumor protein p63 regulated 1 like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:3566888-3567731 Neighboring gene WD repeat containing, antisense to TP73 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 122 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 61 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 62 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 63 Neighboring gene TP73 antisense RNA 3 Neighboring gene tumor protein p73

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_088905.1 

    Range
    101..763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    3625389..3626051
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    3135484..3136146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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