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LOC127271836 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:228556115-228556682 [ Homo sapiens (human) ]

Gene ID: 127271836, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127271836
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:228556115-228556682
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127271836 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (228368414..228368981)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (227557252..227557819)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (228556115..228556682)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904536 Neighboring gene OBSCN antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1916 Neighboring gene obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF Neighboring gene uncharacterized LOC124904535 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228503020-228503894 Neighboring gene Sharpr-MPRA regulatory region 4086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228538867-228539366 Neighboring gene uncharacterized LOC101927401 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:228555546-228556114 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:228557329-228557895 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:228557896-228558461 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2693 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228578692-228579248 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228579249-228579804 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228587477-228588152 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228589505-228590179 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1917 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1918 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1919 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2694 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:228595439-228596098 Neighboring gene uncharacterized LOC124904537 Neighboring gene tripartite motif containing 11 Neighboring gene microRNA 6742 Neighboring gene tripartite motif containing 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_093687.1 

    Range
    101..668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    228368414..228368981
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    227557252..227557819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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