U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127272184 H3K4me1 hESC enhancer GRCh37_chr1:245775221-245775721 [ Homo sapiens (human) ]

Gene ID: 127272184, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
LOC127272184
Gene description
H3K4me1 hESC enhancer GRCh37_chr1:245775221-245775721
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (245611919..245612419)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (245029277..245029775)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (245775221..245775721)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene kinesin family member 26B Neighboring gene ReSE screen-validated silencer GRCh37_chr1:245474556-245474731 Neighboring gene DnaJ heat shock protein family (Hsp40) member C19 pseudogene 8 Neighboring gene Sharpr-MPRA regulatory region 12100 Neighboring gene NANOG hESC enhancer GRCh37_chr1:245629563-245630064 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:245630817-245632016 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr1:245647215-245647978 Neighboring gene uncharacterized LOC124904571 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:245746285-245747484 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245769345-245770175 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245774720-245775220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245786008-245786527 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245811797-245812310 Neighboring gene uncharacterized LOC105373265 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245874319-245874820 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245874821-245875320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:245878266-245878766 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:245926173-245926700 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:245937857-245938697 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:245938698-245939538 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2850 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2851 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:245979520-245980135 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:245980136-245980750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:246016290-246016790 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:246016791-246017291 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:246032999-246034198 Neighboring gene SET and MYND domain containing 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:246111472-246111972 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2852 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:246226795-246227321 Neighboring gene NANOG hESC enhancer GRCh37_chr1:246228833-246229369 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:246273353-246273854 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:246273855-246274354 Neighboring gene Sharpr-MPRA regulatory region 4643 Neighboring gene SMYD3 antisense RNA 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_094035.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    245611919..245612419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187516.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    306223..306723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    245029277..245029775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases