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LOC127272307 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1690638-1691152 [ Homo sapiens (human) ]

Gene ID: 127272307, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127272307
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1690638-1691152
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127272307 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (1686866..1687380)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (1694770..1695284)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1594967-1595486 Neighboring gene uncharacterized LOC124907722 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1595487-1596006 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1596007-1596524 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1598354-1598996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1598997-1599638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1602163-1602662 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1608495-1609288 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1618697-1619416 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:1624935-1625514 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1629027-1629856 Neighboring gene uncharacterized LOC124907723 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1640917-1641511 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1643345-1644278 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1661268-1661929 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1681235-1682160 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1690124-1690637 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1696267-1696766 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1698687-1699427 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1708903-1709506 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1708299-1708902 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1711357-1712002 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1712003-1712647 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1713293-1713937 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1714484-1714990 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1714991-1715497 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1716916-1717895 Neighboring gene peroxidasin Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1731880-1732562 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1732563-1733245 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr2:1734173-1734778 Neighboring gene uncharacterized LOC124907724 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1755052-1755552 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1784798-1785298 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1785299-1785799 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:1805517-1806018 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:1806019-1806518 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:1807745-1808377 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1820106-1821018 Neighboring gene uncharacterized LOC124905967 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:1829865-1830422 Neighboring gene myelin transcription factor 1 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_094158.1 

    Range
    101..615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    1686866..1687380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    1694770..1695284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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