U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127399409 H3K4me1 hESC enhancer GRCh37_chr3:186674568-186675068 [ Homo sapiens (human) ]

Gene ID: 127399409, updated on 27-Aug-2024

Summary

Go to the top of the page Help
Gene symbol
LOC127399409
Gene description
H3K4me1 hESC enhancer GRCh37_chr3:186674568-186675068
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (186956780..186957280)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (189774597..189775097)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:186626722-186627417 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:186627418-186628112 Neighboring gene ribosomal protein S20 pseudogene 14 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:186647930-186648538 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14990 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20946 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20947 Neighboring gene ribosomal protein L29 pseudogene 9 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:186659211-186659712 Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr3:186673829-186674071 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20948 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:186681641-186682220 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:186693287-186694168 Neighboring gene uncharacterized LOC124906314 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20949 Neighboring gene Sharpr-MPRA regulatory region 11729 Neighboring gene Sharpr-MPRA regulatory region 4195 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14991 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20951 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:186716158-186717048 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr3:186717049-186717939 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20953 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20954 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20952 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20955 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20956 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20957 Neighboring gene ST6GAL1 promoter P2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20958 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14992 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20959 Neighboring gene ST6GAL1 promoter P1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20960 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20961 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20962 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20963 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14993 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:186789896-186790855 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20964 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20965 Neighboring gene ribosomal protein L39 pseudogene 19 Neighboring gene ribosomal protein L39 like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_101375.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    186956780..186957280
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    189774597..189775097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases