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LOC127399457 H3K4me1 hESC enhancer GRCh37_chr3:189526229-189526775 [ Homo sapiens (human) ]

Gene ID: 127399457, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127399457
Gene description
H3K4me1 hESC enhancer GRCh37_chr3:189526229-189526775
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127399457 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (189808440..189808986)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (192625090..192625636)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (189526229..189526775)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene tumor protein p63 regulated 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr3:188956266-188957465 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20977 Neighboring gene TPRG1 antisense RNA 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20978 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20979 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:189041855-189043054 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20980 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20981 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:189166776-189167320 Neighboring gene uncharacterized LOC105374270 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20982 Neighboring gene TAp63 promoter of tumor protein p63 Neighboring gene tumor protein p63 Neighboring gene DeltaNp63 promoter of tumor protein p63 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14997 Neighboring gene microRNA 944 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr3:189652551-189653750 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr3:189655039-189656238 Neighboring gene methylthioadenosine phosphorylase pseudogene 2 Neighboring gene prolyl 3-hydroxylase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_101423.1 

    Range
    101..647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    189808440..189808986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    192625090..192625636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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