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LOC127400281 NANOG-H3K4me1 hESC enhancer GRCh37_chr4:8838985-8839598 [ Homo sapiens (human) ]

Gene ID: 127400281, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127400281
Gene description
NANOG-H3K4me1 hESC enhancer GRCh37_chr4:8838985-8839598
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127400281 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (8837259..8837872)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (8804188..8804801)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900659 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8608601-8609168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8609169-8609736 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:8618505-8618698 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8632034-8632534 Neighboring gene carboxypeptidase Z Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8655353-8655869 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8691763-8692264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8696486-8697142 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8703017-8703985 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8707175-8707921 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8707922-8708668 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8711370-8712145 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8725118-8725618 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8725619-8726119 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8727547-8728159 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8728926-8729631 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8731043-8731746 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8746853-8747380 Neighboring gene uncharacterized LOC101928532 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8764548-8765048 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8765049-8765549 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8766906-8767766 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8773080-8773597 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8819142-8819928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8858613-8859157 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8859158-8859701 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8860247-8860789 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8861378-8861996 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8861997-8862614 Neighboring gene H6 family homeobox 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8893515-8894514 Neighboring gene olfactory receptor family 7 subfamily E member 85B pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_102245.1 

    Range
    101..714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    8837259..8837872
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_021159993.1 Reference GRCh38.p14 PATCHES

    Range
    90042..90655
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    8804188..8804801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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