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LOC127402142 H3K27ac hESC enhancer GRCh37_chr4:190862333-190862832 [ Homo sapiens (human) ]

Gene ID: 127402142, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127402142
Gene description
H3K27ac hESC enhancer GRCh37_chr4:190862333-190862832
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127402142 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (189941178..189941677)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (193306163..193306662)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene FRG1 divergent transcript Neighboring gene uncharacterized LOC105377619 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:190749322-190749822 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:190749823-190750323 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:190767193-190767906 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:190767907-190768620 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr4:190802184-190803383 Neighboring gene long intergenic non-protein coding RNA 1596 Neighboring gene FSHD region gene 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:190896381-190896551 Neighboring gene MLLT10 pseudogene 2 Neighboring gene tubulin beta 7 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_104101.1 

    Range
    101..600
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    189941178..189941677
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_015495300.1 Reference GRCh38.p14 PATCHES

    Range
    34108..34607
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_015495301.1 Reference GRCh38.p14 PATCHES

    Range
    34108..34607
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187650.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    278708..279207
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    193306163..193306662
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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