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LOC127405566 H3K27ac hESC enhancer GRCh37_chr6:26053937-26054558 [ Homo sapiens (human) ]

Gene ID: 127405566, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127405566
Gene description
H3K27ac hESC enhancer GRCh37_chr6:26053937-26054558
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127405566 in Genome Data Viewer
Location:
chromosome: 6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (26053709..26054330)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (25921872..25922493)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24184 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24185 Neighboring gene H2A clustered histone 5, pseudogene Neighboring gene H3 clustered histone 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:26053365-26053538 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:26055179-26055800 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24186 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24187 Neighboring gene H1.2 linker histone, cluster member Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17000 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:26066841-26067340 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:26075238-26075738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:26075739-26076239 Neighboring gene HFE antisense RNA 1 Neighboring gene homeostatic iron regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_107537.1 

    Range
    101..722
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    26053709..26054330
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    25921872..25922493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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