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LOC127456876 OCT4-NANOG hESC enhancer GRCh37_chr7:78598351-78598852 [ Homo sapiens (human) ]

Gene ID: 127456876, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127456876
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr7:78598351-78598852
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127456876 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (78969035..78969536)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (80220969..80221470)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 2 Neighboring gene uncharacterized LOC124901683 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:78094936-78095436 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:78095437-78095937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:78127410-78127910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:78127911-78128411 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:78152989-78153548 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:78192436-78193031 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:78206961-78207460 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:78207790-78208526 Neighboring gene UFC1 pseudogene 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:78416757-78417956 Neighboring gene MAGI2 antisense RNA 2 Neighboring gene RNA, U6 small nuclear 337, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_111651.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    78969035..78969536
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    80220969..80221470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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