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LOC127818314 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:73550045-73550944 [ Homo sapiens (human) ]

Gene ID: 127818314, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127818314
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:73550045-73550944
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127818314 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (71790288..71791187)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (72661015..72661914)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (73550045..73550944)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene cadherin related 23 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:73476810-73477007 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:73478924-73479672 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:73485282-73486481 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:73489247-73489438 Neighboring gene chromosome 10 open reading frame 105 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3518 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3519 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3520 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:73517352-73517887 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:73526094-73527293 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2465 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2466 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:73537763-73537918 Neighboring gene V-set immunoregulatory receptor Neighboring gene Sharpr-MPRA regulatory region 2121 Neighboring gene uncharacterized LOC124902446 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:73570820-73571322 Neighboring gene microRNA 7152 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:73595633-73596402 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:73596403-73597172 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:73597943-73598711 Neighboring gene prosaposin Neighboring gene RNA, U7 small nuclear 38 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_119787.1 

    Range
    101..1000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    71790288..71791187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    72661015..72661914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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