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LOC127826360 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:53421849-53422738 [ Homo sapiens (human) ]

Gene ID: 127826360, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127826360
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:53421849-53422738
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127826360 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (52847714..52848603)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (52063159..52064048)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:53412585-53413086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:53413087-53413586 Neighboring gene microRNA 759 Neighboring gene peptidylprolyl isomerase A pseudogene 26 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:53420960-53421848 Neighboring gene Sharpr-MPRA regulatory region 8019 Neighboring gene Sharpr-MPRA regulatory region 8029 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7796 Neighboring gene protocadherin 8 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:53453690-53454319 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:53454320-53454948 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:53480206-53480776 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7797 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:53499618-53500118 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:53530858-53531358 Neighboring gene olfactomedin 4 Neighboring gene long intergenic non-protein coding RNA 1065

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_127867.1 

    Range
    101..990
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    52847714..52848603
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    52063159..52064048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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